Renal news roundup from AKF

The FDA has reported 76 cases of drug-induced liver injury linked to Amgen's rare disease drug Tavneos, including eight deaths. The agency has asked Amgen to pull the drug from the market, but the company has resisted. Most cases were reported in Japan, with a few in the US, Euro...

Iptacopan (Fabhalta) has significantly slowed the decline of kidney function in adults with immunoglobulin A nephropathy (IgAN), according to final results from the Phase III APPLAUSE-IgAN study published in the New England Journal of Medicine. Over 24 months, the annualized tota...

Biogen has agreed to acquire Apellis Pharmaceuticals for $5.6 billion to diversify its portfolio and strengthen its presence in nephrology. The deal includes two approved drugs, Empaveli and Syfovre, and brings the expertise of Apellis' team to support the launch of felzartamab, ...

A study published in Communications Medicine found that COVID-19 poses a significantly higher risk of kidney disease than influenza among working-age adults in the U.S. The research analyzed data from over 3 million individuals, showing that COVID-19 is associated with increased ...

University of Cincinnati College of Medicine researchers noted a bidirectional relationship between gum disease and CKD, with the conditions sharing inflammatory pathways that can worsen each other. The study highlights the importance of integrating dental care into overall medic...

A study in the American Journal of Transplantation found that kidney transplantation as an initial treatment for patients with severe aplastic anemia and ESRD may improve hematologic outcomes. Researchers observed stable kidney function and significant hematologic improvement in ...

A study presented at an American Heart Association meeting found that elevated blood pressure between ages 30 and 40 was associated with a higher risk of heart and kidney disease. The research, involving 291,887 participants, found that systolic blood pressure above 120 mm Hg was...

The urinary albumin-to-creatinine ratio is more strongly associated with adverse outcomes than the urine protein-to-creatinine ratio in children with CKD, according to a study in Nephrology Dialysis Transplantation. The findings support prioritizing UACR for risk stratification i...

Annual employment income increases for adults with ESRD after kidney transplants, according to a study published in JAMA Network Open. The research, involving Canadian adults, finds income declines three years before a transplant, but rises during the transplant year and three ye...